Abstract:
Two compounds having the capsaicin derivative structure of acrylamide, N-(3-tert-butyl-2-hydroxy-5-methylbenzyl )acrylamide (MBHBA)and N-(3-tert-butyl-2-hydroxy-5-methylbenzyl) benzamide (MBHBB) were synthesized the structure of which were characterized by FT-IR spectroscopy and HNMR. Comparison of the antibacterial and antifouling properties of the MBHBA and MBHBB showed that two compounds were good on suppression of staphyloccocus aureus and escherichia colit, and the minimal inhibitory concentration of MBHBA was 0. 125 mg/mL. With MBHBA and MBHBB antifouling agent for preparation of marine antifouling coatings, test panels immersed in seawater for 60 days showed that MBHBB and MBHBA exhibited equally good anti-biofouling performance.
Key words:
2-t-butyl-p-cresol,
synthesis,
bacterium-inhibition,
antifoulant
摘要： 通过Friedel-Crafts反应合成了N-(5-甲基-3-叔丁基-2-羟基苄基)丙烯酰胺(MBHBA)和N-(5-甲基-3-叔丁基-2-羟基苄基)苯甲酰胺(MBHBB),并通过红外光谱(FT-IR)和核磁波谱(1HNMR)对其结构进行了表征。对比了MBHBA和MBHBB的抑菌性能和防污性能,结果显示2种化合物均有良好的抑制金黄色葡萄球菌和大肠杆菌的性能,且MBHBA的最小抑菌浓度可达0.125 mg/mL;以MBHBA和MBHBB为防污剂制备海洋防污涂料,60 d的实海挂板仍无明显的污损生物附着。
关键词:
2-叔丁基对甲基酚,
合成,
抑菌,
防污性能
Zhang Zhijia, Yu Liangmin, Jiang Xiaohui. Synthesis and the Bacteriostasic Activity and Antifouling Capability of 2-t-Butyl-p- Cresol Amide Derivatives[J]. Paint & Coatings Industry, 2012, 42(12): 20-23.
张智嘉, 于良民, 姜晓辉. 2-叔丁基对甲基酚酰胺衍生物的合成及其抑菌和防污性能的研究[J]. 涂料工业, 2012, 42(12): 20-23.