［Objective/Significance］ Anti-fingerprint agents have important applications in protecting the surface of touch screens.［Analysis/Discussion/Progress］Based on the mechanism of anti-fingerprint agents，the molecular design concept of anti-fingerprint agent was expounded from amolecular structure perspective. In light of market demand，the preparation methods for two categories of functional anti-fingerprint agents were introduced，and the preparation techniques of anti-fingerprint coatings were also summarized.［Conclusion/Prospect］The market demand for high-end functional anti-fingerprint coatings is expected to increase steadily. Although domestic research on anti-fingerprint agents has achieved systematic progress in molecular structure design and functionalproduct development，challenges persist，including reliance on imported key raw materials and a limited share in the high-end market. Future efforts should focus on technological breakthroughs for raw materials self-sufficiency，precise molecular design，innovation in functional products，and optimization of coating processes，thereby promoting domestic substitution and industrial upgrading.