［Objective/Significance］Ice accretion often compromises the performance and safetyof outdoor facilities，making the development of highly efficient anti-icing coatings becomes a topic ofwidespread interest in both scientific and industrial communities. Cold-tolerant organisms，through natural evolution and selection，have developed diverse anti-icing strategies，providing a novel approach for developing highly efficient bio-inspired anti-icing coatings.［Analysis/Discussion/ Progress］This review begins by summarizing recent research on anti-icing strategies in cold-tolerant organisms，with a focus on the mechanisms underlying the ice resistance of penguin feathers，polar bear fur，and antifreeze proteins（AFPs）. Subsequently，representative cases of bio-inspired anti-icingcoating are introduced and discussed. Furthermore，based on the concept of“skin-like materials”，recent advances in self-healing anti-icing coating are highlighted.［Conclusion/Prospect］ The biomimetic study of anti-icing strategies from cold-tolerant organisms is an emerging frontier. Utilizinganti-icing biomolecules（e. g.，antifreeze proteins）offers a highly promising approach for constructinghighly efficient anti-icing coating. Future efforts should focus on enriching the underlying theory，better integrating biomimetic designs，and leveraging synthetic biology to create advanced anti-icing biomolecules，thus expediting the commercialization of bio-inspired anti-icing coating.