［Objective/Significance］ Silicate-based cultural relics hold significant historical， artistic，and scientific value，and their conservation is crucial for the transmission of cultural heritage.The use of silicone materials for the protection and reinforcement of silicate-based relics serves as adirect and effective method to mitigate deterioration and improve preservation conditions，demonstrating remarkable research and application value.［Analysis/Discussion/Progress］Based on the unique chemical structure and superior properties of silicone materials，this study elaborated on their protection and reinforcement mechanisms for silicate-based relics. It reviewed the research and application progress of siloxanes and their composites，silicone-modified acrylic resins，nanomaterials， epoxy resins，and biomimetic synthetic materials in the conservation of silicate-based relics. Additionally，it discussed existing challenges in practical research and applications，along with potential solutions.［Conclusion/Prospect］Silicone materials exhibit excellent compatibility with silicate substrates and leverage the synergistic advantages of multiple materials，making them an ideal choice for the protection and reinforcement of silicate-based relics. However，they still face challenges such as poor penetration，salt enrichment damage，and aging-induced failure. Future research should focus on developing highly targeted materials，exploring eco-friendly biomimetic synthesis approaches， and enhancing material permeability and interfacial stress resistance.