［Objective］To address the issue of traditional coatings being prone to failure in human sweat environments，cathodic electrophoretic coatings with high resistance to artificial sweat wasprepared using acrylic resins.［Methods］By screening the types and amounts of acrylic monomers，the effects of curing agent dosage，neutralization degree，electrophoretic construction，and curing process parameters on coating performance were studied，a coating with excellent sweat corrosion resistance wasobtained. The structure of the product was characterized by Fourier transform infrared spectrometer（FT-IR）.［Results］The results indicated controlling the amount of monomer GMA in resin synthesis to be 11%-12%，the amount of MMA to be 25%-30%，the amount of IBOMA to be 12%-15%，the amount of other functional monomers，and the key influencing factors during the coating construction process，a coating system with excellent comprehensive performance was obtained，and the artificial sweat resistance was more than 96 hours，which was significantly better than similar products.［Conclusion］This product was applicated in surface protection for automotive interior components， sports equipment，and accessories such as eyewear and watches.