In order to develop and apply natural jade tailing on a large scale and give fullplay to the environmental functions of jade tailing，this article aimed to develop waterbornefunctional building coatings for indoor building with natural jade tailing materials. Jade tailingpowder from the Xiuyan area was selected as the raw material. The safety and applicationperformance in coatings of natural jade tailing were studied. Waterborne building coatingswere prepared with low heat treatment jade tailing powder with high activity and raw jadetailing powder. And the physical performance，environmental performance and antimicrobialfunction of the coating system were evaluated. The results showed that the low-temperatureheat treatment jade tailing and raw jade tailing powder both had good compatibility with thecoating. And the whiteness，pH value，and safety completely could meet the requirements ofbuilding coatings. The coating prepared by 270 ℃ heat treatment jade tailing powder was alsogood at anti-bacterial performance with 99. 9% rate.