To improve the sound insulation performance of the coating，hollow glass microspheres（HGM）and alumina microspheres were selected as fillers to study the effect ofdifferent types of functional fillers on the sound insulation performance of waterborne epoxycoatings. Surface-treated HGM was uniformly distributed in the coating to test the relationshipbetween the sound transmission loss（TL）and the amount of HGM，and on the basis of the above study，small-sized alumina microspheres were further added to study their filling rolebetween the voids of the HGM stack. The results showed that the average TL of the coatingwith 15% HGM was improved by 5% compared with that of the aluminum foil substrate；the addition of alumina could play a role in filling and reducing the fragmentation of HGM. The coating with 15% HGM and 12% Al₂O₃ had a better sound isolation effect in the frequency band of 2 000-4 000 Hz，and the average TL of the coating was further improved by 3%compared with that of the coating with only 15% HGM，and had a better performance on thetransmission loss of the specific sound generating equipment in the 40-80 dB sound pressurelevel range of noise，compared with the transmission loss of aluminum foil substrate increasedby 6 dB. This study provided a valuable reference for the development of environmentallyfriendly coatings with sound insulation effects for the equipment such as mechanical pumps， compressors，and motors.