【目的】开发绿色环保的抗菌树脂。【方法】通过引入具有本征杀菌活性的生物基呋喃官能化扩链剂，设计并制备了一种绿色环保型本征抗菌聚肟氨酯弹性体（PCDU）。【结果】该材料在保持优异力学性能（拉伸强度达 4. 03 MPa，断裂伸长率达 430%）的基础上，展现出色的抗菌性能（24 h抗菌率 100%）和抗黏附性能（藻和蛋白黏附率几乎为 0）。【结论】制备了一种绿色环保的本征抗菌聚肟氨酯，为后续开发海洋本征抗菌涂料提供一定参考。

［Objective］ To develop green and environment-friendly antibacterial resin.［Methods］Herein，we report the design and synthesis of a green，intrinsically antifouling polyoxime urethane elastomer（PCDU）by incorporating a bio-based，furan-functionalized chain extender with inherent antibacterial activity.［Results］ The resulting PCDU exhibits outstanding mechanical properties（tensile strength up to 4. 03 MPa and elongation at break of 430%）， along with excellent antibacterial efficacy（100% inhibition within 24 h）and antifouling performance（nearly zero adhesion of algae and proteins）.［Conclusion］ A green and environment-friendly intrinsically antibacterial polyoxime urethane was prepared，which provided a certain reference value for the subsequentdevelopment of intrinsically antibacterial marine coatings.