【目的】采用自制的 KH550修饰纳米银颗粒（AgNPs）作为抗菌剂，开发一种高效抗菌水性内墙涂料。【方法】以硝酸银水溶液为银源，γ-氨丙基三乙氧基硅烷（KH550）为表面修饰剂，1，2-丙二醇为溶剂和还原剂，通过溶液化学方法制备了 KH550修饰的纳米银颗粒（AgNPs）。随后，将 AgNPs按照不同比例添加到水性内墙涂料中制备抗菌涂层。利用紫外-可见分光光度计、X射线光电子能谱仪和透射电子显微镜对 AgNPs的光学性能、化学组成和形貌进行了表征，并系统测试了涂层的抗菌性能。【结果】AgNPs对革兰氏阴性大肠杆菌和革兰氏阳性金黄色葡萄球菌均表现出优异的抗菌性能。当 AgNPs分散液的添加比例达 1. 05%时，抗菌涂层对大肠杆菌的抗菌率达到 100%，对金黄色葡萄球菌的抗菌率达到 99. 1%。【结论】本研究通过 KH550表面修饰的 AgNPs，成功制备出高效抗菌水性内墙涂料。其抗菌性能与 AgNPS添加量呈正相关，1. 05%添加比例下可实现广谱抗菌效果，为建筑涂料的抗菌功能化提供了可行方案。

［Objective］The purpose of this study was to develop efficient antibacterial waterborneinterior wall coatings. By using self-made KH550 surface modified silver nanoparticles（AgNPs）as an antibacterial agent，a coatings product with excellent antibacterial properties was successfully prepared.［Methods］ Using silver nitrate aqueous solution as silver source，γ -aminopropyltriethoxysilane（KH550）as surface modifier，1，2-propylene glycol as solvent and reducing agent，KH550 surface modified silver nanoparticles（AgNPs） were prepared by solution chemical method. During the experiment，AgNPs were successfully synthesized using 1，2-propanediol as solvent and reducingagent，and 0. 1 mol/L silver nitrate aqueous solution as silver source. Subsequently，different proportions of AgNPs dispersion were added to the waterborne coatings，and the antibacterial coatings were cured by volatile solvents. The optical properties，chemical composition and morphology of AgNPswere characterized by ultraviolet-visible absorption spectroscopy（UV-Vis），X-ray photoelectron spectroscopy（XPS）and transmission electron microscopy（TEM），and the antibacterial properties of the coatings were systematically evaluated.［Results］ AgNPs exhibited excellent antibacterial properties against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. When the addition amount of AgNPs dispersion reached 1. 05%，the antibacterial rate of the antibacterial coatings against Escherichia coli reached 100%，and the antibacterial rate against Staphylococcus aureus reached 99. 1%.［Conclusion］In this study，high-efficiency antibacterial waterborne interior wall coatings was successfully prepared by KH550 surface-modified AgNPS. The antibacterial performance was positively correlated with the amount of AgNPS added. The broad-spectrum antibacterial effect couldbe achieved at the addition amount of 1. 05%，which provided a feasible solution for the antibacterial functionalization of architectural coatings.