【目的】解决海洋领域中光学仪器窗口在服役过程中存在海洋污损生物附着的负面影响。【方法】以 3，3，3-三氟丙基甲基二甲氧基硅烷（ MTFPS）为单体，通过酸催化缩聚在玻璃表面共价接枝了主链硅氧键的类液态分子刷超滑表面。表征了分子刷超滑表面结构和形貌，并研究了超滑表面的拒液性、透光性、稳定性以及对蛋白、细菌和藻类的防污性能。【结果】通过化学键合形成的类液态分子刷超滑表面透光度高，并且具有优异的拒液性，可有效避免液体对表面的润湿；对牛血清蛋白、大肠杆菌、金黄色葡萄球菌以及小球藻和三角褐指藻都表现出优异的防黏附性能。【结论】本研究为应用于海洋领域中光学仪器窗口的防污技术的开发提供了新的思路和策略。

［Objective］This study aims to mitigate the adverse effects caused by the adhesion ofmarine fouling organisms to the windows of optical instruments during their service in the marineenvironment.［Methods］ Using 3，3，3-trifluoropropylmethyldimethoxysilane（MTFPS） as the monomer，a liquid-like molecular brush slippery surface which featuring a main chain composed ofsiloxane bonds was prepared via covalent grafting on the surface of glass substrate through acid-catalyzed polycondensation. The structure and morphology of the molecular brush slippery surface werecharacterized systematically. Additionally，key performances of the slippery surface were investigated， including liquid repellency，light transmittance，stability，and anti-fouling efficacy against proteins， bacteria，and algae.［Results］The liquid-like molecular brush slippery surface formed by chemicalbonding exhibits excellent liquid repellency，which can effectively prevent liquid from wetting thesurface and maintain high light transmittance. Furthermore，the surface-bonded liquid-like molecularbrush demonstrates superior anti-adhesion performance against bovine serum albumin，Escherichia coli，Staphylococcus aureus，Chlorella pyrenoidosa and Phaeodactylum tricornutum.［Conclusion］This work provides novel insights and strategies for the development of anti-fouling technologies tailored tothe windows of optical instruments in the marine field.